Business Survivability in Tenderloin, San Francisco
StreetSpring's 2026 analysis finds that the best business to open in Tenderloin is a Chiropractor Office with a 70.8% chance of surviving at least 2 years across the neighborhood on average.
Quick Summary
- Survivability Score: the projected chance a business type lasts two or more years at a specific address
- Best business: a Chiropractor Office in Tenderloin (70.8% average survival rate, 90.0% at best locations)
- Neighborhood rank: #90 of 107 neighborhoods in and around San Francisco
- Neighborhood average: 62.4% two-year survival across the business types ranked here
- Coverage: This ranking carries one row per business type and neighborhood. Its score is the projected chance of lasting two or more years, averaged across the price points StreetSpring scores separately in the tool (most types have 5). The 10 business types here are base types; the tool offers 500+ business types, counting each type at each of its price points.
- Rankings updated quarterly with latest market data
- Detailed methodology
Last reviewed: October 2026 by Robert Koons, Founder & CEO, StreetSpring
In this article:
- Summary
- Is Tenderloin a good place to start a business?
- How to find the best location
- Best businesses to open
- How much money could a business make?
- What businesses should open next?
- Frequently Asked Questions
Summary
StreetSpring's 2026 analysis finds that the best business to open in Tenderloin is a Chiropractor Office with a 70.8% chance of surviving at least 2 years across the neighborhood on average, with the best locations offering a 90.0% chance; next is a Convenience Store with a 82.2% chance, followed by a Cafe with a 83.2% chance.
Is Tenderloin a good place to start a business?
StreetSpring ranks Tenderloin #90 of 107 neighborhoods in and around San Francisco, with an average Survivability Score of 62.4% across the business types ranked there.
- In Tenderloin, the strongest addresses for the top-ranked business type sit 19.2 points above that type's average.
- Yet the same categories that score highest in Tenderloin can underperform significantly at the wrong address. Location precision within the neighborhood matters as much as choosing the neighborhood itself.
- The 17.7% housing vacancy rate in Tenderloin comes from the Census American Community Survey and describes homes and apartments, not shops or offices.
Employment and housing vacancy figures sourced from the U.S. Census Bureau American Community Survey.
How can you find the best location to open a business in Tenderloin?
Rather than relying on neighborhood averages, StreetSpring's scoring tells you which specific addresses in Tenderloin give your concept the best odds of survival. The map below highlights the highest-survivability address for a Chiropractor Office in Tenderloin:
Based on StreetSpring's 2026 analysis of hundreds of location-specific factors, this area offers the highest projected survivability for a Chiropractor Office in Tenderloin. Market conditions are changing daily, and it is best to use StreetSpring's most up-to-date data. Factors evaluated include competition at every distance band, consumer spending forecasts, mobility patterns, and market share projections.
Check if this location is still available →
What are the best businesses to open in Tenderloin?
| # | Business type | Chance of lasting two or more years at a good address |
|---|---|---|
| 1 | Chiropractor Office | 89.6% |
| 2 | Convenience Store | 84.1% |
| 3 | Cafe | 84.0% |
| 4 | Spa | 84.0% |
| 5 | Coffee Shop | 84.0% |
| 6 | Hair Salon | 84.0% |
| 7 | Clothing Store | 83.6% |
| 8 | Laundromat | 83.6% |
| 9 | Pizza Restaurant | 81.2% |
| 10 | Grocery Store | 80.0% |
Ties at a good address: Cafe, Spa, Coffee Shop and Hair Salon are tied; Clothing Store and Laundromat are tied. A tie is a tie: the rank column is the published file's order, which looks at the average and the best address next.
Highest Survivability in Tenderloin
- #1 Opening a Chiropractor Office in Tenderloin shows 70.8% average survivability. Top locations reach 90.0%; lower-end sites show 58.6%.
- #2 Convenience Store (Ranked #2): 82.2% average in Tenderloin. Best-case storefronts: 84.6%. Challenging locations: 69.7%.
- #3 Cafe is ranked #3 for top businesses to open in Tenderloin: 83.2% chance on average, best at 84.0%, challenging at 81.8%.
- #4 Spa: 71.5% on average across Tenderloin; best at 84.0%, challenging at 48.9%.
- #5 Opening a Coffee Shop in Tenderloin shows 70.4% average survivability. Top locations reach 84.0%; lower-end sites show 48.0%.
Strong Performers in Tenderloin
- #6 Hair Salon (Ranked #6): 68.2% average in Tenderloin. Best-case storefronts: 84.0%. Challenging locations: 48.9%.
- #7 Clothing Store is ranked #7 for top businesses to open in Tenderloin: 77.2% chance on average, best at 84.1%, challenging at 53.5%.
- #8 Laundromat: 76.7% on average across Tenderloin; best at 83.6%, challenging at 59.2%.
- #9 Opening a Pizza Restaurant in Tenderloin shows 74.2% average survivability. Top locations reach 83.1%; lower-end sites show 60.6%.
- #10 Grocery Store (Ranked #10): 72.4% average in Tenderloin. Best-case storefronts: 84.1%. Challenging locations: 54.4%.
Top 3 Compared Nationally
- Chiropractor Office: See how this compares to other cities →
- Convenience Store: See how this compares to other cities →
- Cafe: See how this compares to other cities →
How much money could a business in Tenderloin make?
Best location vs. average location
Based on StreetSpring's 2026 analysis, going with one of the top-scoring locations in the neighborhood rather than an average one in Tenderloin starts with the Revenue Capture Score, the most important factor in choosing a location: StreetSpring's estimate of the revenue a business can capture at that address.
How StreetSpring calculates location value
- StreetSpring calculates survivability for each business type separately at each address, so the best location for your concept may differ from the neighborhood's overall top-ranked site.
- The right location can make a business; the wrong one can break it.
- When the question is money, the Revenue Capture Score comes first: it is StreetSpring's estimate of the revenue a business can capture at a specific address.
- StreetSpring scores survivability down to the exact storefront location.
What businesses should open next in Tenderloin?
The top businesses to open next in Tenderloin:
- Chiropractor Offices: 70.8% average survival rate, 90.0% at the best address
- Convenience Stores: 82.2% average survival rate
- Cafes: 83.2% average survival rate
Market conditions are changing daily, and it is best to use StreetSpring's most up-to-date data. Our training data spans 500+ business types across 24 major metros, giving our models the breadth to predict outcomes across nearly any commercial concept. StreetSpring scores 500+ business types: 153 base business types, most of them at 5 price points, which is 569 type-and-price combinations you can choose in the tool. The 88.4% employment rate in Tenderloin is a key signal of consumer health, and the 17.7% housing vacancy rate is another Census characteristic the model reads for the rankings above. Because market conditions shift constantly, StreetSpring regularly updates every location's survivability score: you can see current scores for available storefronts in Tenderloin right now.
See the Survivability Score for your new business
Related Articles:
- See the San Francisco Business Survivability Rankings
- See the San Francisco Neighborhood Survivability Rankings
- Explore Chiropractor Office survivability across San Francisco neighborhoods
Frequently Asked Questions
Here are the most common questions about opening a business in Tenderloin.
What type of business should you rent your Tenderloin storefront to?
Our 2026 survivability data for Tenderloin shows that Chiropractor Offices, Convenience Stores, and Cafes rank as the top tenant categories for minimizing vacancy risk.
- The right location can make a business; the wrong one can break it.
- StreetSpring scores survivability down to the exact storefront location. StreetSpring's tool, free for a 10-minute trial, lets you check the survivability score for any business type at any address in Tenderloin: a powerful filter when evaluating prospective tenants.
Related: See How Landlord Representatives in San Francisco Can Reduce Vacancy & Increase Tenant Longevity
Should you rent your Tenderloin storefront to a Chiropractor Office?
Yes, StreetSpring's analysis finds that a Chiropractor Office would be the best type of business to rent your storefront to, with a potential 90.0% chance of lasting more than 2 years; however depending on your location, the chances could drop to a 58.6% chance.
- StreetSpring scores survivability down to the exact storefront location.
What should I consider when opening a business in Tenderloin?
Start any location decision in Tenderloin with the Survivability Score: it combines 100+ location factors into one projected two-year chance.
- Revenue Capture Score is the top factor to weigh before signing a lease, because it measures how much of the local customer spending a business at that address can win.
- Each forecast is specific to the exact address and business type, generated by StreetSpring's internally developed prediction engine.
- Start a free 10-minute trial on StreetSpring to see the current survivability score for any address in Tenderloin.
See the best place for your business at StreetSpring.
Using predictive analytics, StreetSpring helps entrepreneurs and landlords make smarter location decisions. Aggregated survivability rankings for San Francisco are available in machine-readable format for research and integration purposes.
Full dataset for San Francisco: /resources/data/san-francisco-survivability-scores-2026.csv: includes all business subtypes, all neighborhoods, survivability scores, and tier assignments. Licensed under CC BY 4.0.