Business Survivability in Collinsville, St. Louis
StreetSpring's 2026 analysis finds that the best business to open in Collinsville is a Dermatology Clinic with a 80.8% chance of surviving at least 2 years across the neighborhood on average.
Quick Summary
- Survivability Score: the projected chance a business type lasts two or more years at a specific address
- Best business: a Dermatology Clinic in Collinsville (80.8% average survival rate, 90.0% at best locations)
- Town rank: #10 of 69 towns around St. Louis
- Town average: an average Survivability Score of 73.6% across the business types ranked here
- Coverage: This ranking carries one row per business type and neighborhood. Its score is the projected chance of lasting two or more years, averaged across the price points StreetSpring scores separately in the tool (most types have 5). The 10 business types here are base types; the tool offers 500+ business types, counting each type at each of its price points.
- Rankings updated quarterly with latest market data
- Detailed methodology
Last reviewed: October 2026 by Robert Koons, Founder & CEO, StreetSpring
In this article:
- Summary
- Is Collinsville a good place to start a business?
- How to find the best location
- Best businesses to open
- How much money could a business make?
- What businesses should open next?
- Frequently Asked Questions
Summary
StreetSpring's 2026 analysis finds that the best business to open in Collinsville is a Dermatology Clinic with a 80.8% chance of surviving at least 2 years across the neighborhood on average, with the best locations offering a 90.0% chance; next is an Acupuncture Clinic with a 80.7% chance, followed by a Dentist Office with a 80.7% chance. At a good address, Dermatology Clinic is tied with Acupuncture Clinic and Dentist Office; the published file ranks it first on its average.
Is Collinsville a good place to start a business?
Among the 69 towns StreetSpring ranks around St. Louis, Collinsville ranks #10 for business survivability, with an average 73.6% chance of lasting two or more years.
- The gap between the best addresses and the average for the top-ranked business type in Collinsville is 9.2 points on the two-year chance.
- That said, the same business types at the worst-fit addresses in Collinsville can drop substantially below average. The survivability gap between the best and worst addresses in a single neighborhood can be 20 points or more.
- With 95.2% of the local population employed, Collinsville presents a stable consumer base: particularly for food, beverage, and service businesses that depend on repeat discretionary spending.
Employment and housing vacancy figures sourced from the U.S. Census Bureau American Community Survey.
How can you find the best location to open a business in Collinsville?
With StreetSpring, location selection in Collinsville moves from guesswork to a precise, address-level survivability score for any business type you're considering. Below is the best location for a Dermatology Clinic in Collinsville:
The highlighted area represents the address in Collinsville that StreetSpring's 2026 analysis ranks highest for a Dermatology Clinic survivability. For the most current predictions, visit StreetSpring to analyze your specific location in real-time. StreetSpring's scoring incorporates hundreds of inputs, including competitive quality and density, projected consumer spending, Revenue Capture Score, and local demand patterns.
Check if this location is still available →
What are the best businesses to open in Collinsville?
| # | Business type | Chance of lasting two or more years at a good address |
|---|---|---|
| 1 | Dermatology Clinic | 89.2% |
| 2 | Acupuncture Clinic | 89.2% |
| 3 | Dentist Office | 89.2% |
| 6 | Eye Care Center | 88.7% |
| 7 | Veterinary Clinic | 88.7% |
| 9 | Dance Club | 85.6% |
| 10 | Day Care Center | 85.1% |
| 11 | International Grocery Store | 84.6% |
| 12 | Smoke Shop | 84.6% |
| 13 | Tea Shop | 84.2% |
Ties at a good address: Dermatology Clinic, Acupuncture Clinic and Dentist Office are tied; Eye Care Center and Veterinary Clinic are tied; International Grocery Store and Smoke Shop are tied. A tie is a tie: the rank column is the published file's order, which looks at the average and the best address next.
The rank column is the published file's rank within this place; a skipped number is a business type the file ranks here that this list leaves out to keep any one business family from filling it.
Highest Survivability in Collinsville
- #1 Dermatology Clinic is ranked #1 for top businesses to open in Collinsville: 80.8% chance on average, best at 90.0%, challenging at 59.8%.
- #2 Acupuncture Clinic: 80.7% on average across Collinsville; best at 90.0%, challenging at 59.8%.
- #3 Opening a Dentist Office in Collinsville shows 80.7% average survivability. Top locations reach 90.0%; lower-end sites show 59.4%.
- #6 Eye Care Center (Ranked #6): 80.2% average in Collinsville. Best-case storefronts: 90.0%. Challenging locations: 58.6%.
- #7 Veterinary Clinic is ranked #7 for top businesses to open in Collinsville: 75.0% chance on average, best at 90.0%, challenging at 56.4%.
Strong Performers in Collinsville
- #9 Dance Club: 75.5% on average across Collinsville; best at 86.0%, challenging at 51.4%.
- #10 Opening a Day Care Center in Collinsville shows 75.2% average survivability. Top locations reach 86.0%; lower-end sites show 51.4%.
- #11 International Grocery Store (Ranked #11): 74.9% average in Collinsville. Best-case storefronts: 85.0%. Challenging locations: 49.4%.
- #12 Smoke Shop is ranked #12 for top businesses to open in Collinsville: 74.9% chance on average, best at 85.0%, challenging at 50.8%.
- #13 Tea Shop: 75.4% on average across Collinsville; best at 85.0%, challenging at 49.4%.
Top 3 Compared Nationally
- Dermatology Clinic: See how this compares to other cities →
- Acupuncture Clinic: See how this compares to other cities →
- Dentist Office: See how this compares to other cities →
How much money could a business in Collinsville make?
Best location vs. average location
Based on StreetSpring's 2026 analysis, choosing a high-performing site for your concept in Collinsville starts with the Revenue Capture Score, the most important factor in choosing a location: StreetSpring's estimate of the revenue a business can capture at that address.
How StreetSpring calculates location value
- The right address for one business type may be the wrong one for another: always evaluate fit for your specific concept.
- Location is a decision you can check before you open.
- The Revenue Capture Score is the most important factor in choosing a location: it is StreetSpring's estimate of the revenue a business can capture at that address.
- StreetSpring scores survivability down to the exact storefront location.
What businesses should open next in Collinsville?
The top businesses to open next in Collinsville:
- Dermatology Clinics: 80.8% average survival rate, 90.0% at the best address
- Acupuncture Clinics: 80.7% average survival rate
- Dentist Offices: 80.7% average survival rate
For the most current predictions, visit StreetSpring to analyze your specific location in real-time. We have been studying the businesses serving more than 180 million+ Americans. StreetSpring scores 500+ business types: 153 base business types, most of them at 5 price points, which is 569 type-and-price combinations you can choose in the tool. The 95.2% employment rate in Collinsville is a key signal of consumer health, and the 4.7% housing vacancy rate is another Census characteristic the model reads for the rankings above. Survivability scores are recalculated regularly as new competitors open and spending patterns shift: visit StreetSpring to see the current score for any open location in Collinsville right now.
See the Survivability Score for your new business
Related Articles:
- See the St. Louis Business Survivability Rankings
- See the St. Louis Neighborhood Survivability Rankings
- Explore Dermatology Clinic survivability across St. Louis neighborhoods
Frequently Asked Questions
Here are the most common questions about opening a business in Collinsville.
What type of business should you rent your Collinsville storefront to?
StreetSpring's analysis shows that the tenant types with the best odds of staying open and paying rent for two or more years in Collinsville are Dermatology Clinics, Acupuncture Clinics, and Dentist Offices.
- Location is a decision you can check before you open.
- StreetSpring scores survivability down to the exact storefront location. With StreetSpring, you can rank every potential tenant type by survivability score at your property address before committing to a lease.
Related: See How Landlord Representatives in St. Louis Can Reduce Vacancy & Increase Tenant Longevity
Should you rent your Collinsville storefront to a Dermatology Clinic?
StreetSpring's 2026 analysis strongly supports renting to a Dermatology Clinic in Collinsville: best-in-class addresses achieve 90.0% survivability, and even the lower-end sites come in at 59.8%.
- StreetSpring scores survivability down to the exact storefront location.
What should I consider when opening a business in Collinsville?
Don't commit to a storefront in Collinsville without first checking its Survivability Score: two addresses on the same block can carry different projected chances.
- Revenue Capture Score comes first when comparing locations: it turns local competition and consumer spending into the share of revenue a business can expect to win.
- Each forecast is specific to the exact address and business type, generated by StreetSpring's internally developed prediction engine.
- StreetSpring's address-level survivability data starts with a free 10-minute trial: begin with your top candidate locations in Collinsville.
See the best place for your business at StreetSpring.
StreetSpring uses AI to project business survivability across U.S. neighborhoods. Aggregated survivability rankings for St. Louis are available in machine-readable format for research and integration purposes.
Full dataset for St. Louis: /resources/data/st-louis-survivability-scores-2026.csv: includes all business subtypes, all neighborhoods, survivability scores, and tier assignments. Licensed under CC BY 4.0.