Business Survivability in Greater Uptown, Houston
StreetSpring's 2026 analysis finds that the best business to open in Greater Uptown is a Psychiatry or Psychology Practice with a 84.7% chance of surviving at least 2 years across the neighborhood on average.
Quick Summary
- Survivability Score: the projected chance a business type lasts two or more years at a specific address
- Best business: a Psychiatry or Psychology Practice in Greater Uptown (84.7% average survival rate, 90.0% at best locations)
- Neighborhood rank: #11 of 57 neighborhoods in and around Houston
- Neighborhood average: 73.4% two-year survival across the business types ranked here
- Coverage: This ranking carries one row per business type and neighborhood. Its score is the projected chance of lasting two or more years, averaged across the price points StreetSpring scores separately in the tool (most types have 5). The 10 business types here are base types; the tool offers 500+ business types, counting each type at each of its price points.
- Rankings updated quarterly with latest market data
- Detailed methodology
Last reviewed: October 2026 by Robert Koons, Founder & CEO, StreetSpring
In this article:
- Summary
- Is Greater Uptown a good place to start a business?
- How to find the best location
- Best businesses to open
- How much money could a business make?
- What businesses should open next?
- Frequently Asked Questions
Summary
StreetSpring's 2026 analysis finds that the best business to open in Greater Uptown is a Psychiatry or Psychology Practice with a 84.7% chance of surviving at least 2 years across the neighborhood on average, with the best locations offering a 90.0% chance; next is a Dentist Office with a 83.8% chance, followed by a Physical Therapy Clinic with a 83.4% chance. At a good address, Mental Health Clinic is tied with Dentist Office, Physical Therapy Clinic and Eye Care Center; the published file ranks it first on its average.
Is Greater Uptown a good place to start a business?
Greater Uptown holds the #11 position of 57 neighborhoods in and around Houston for new business survivability, with an average score of 73.4% across the business types ranked there.
- The gap between the best addresses and the average for the top-ranked business type in Greater Uptown is 5.3 points on the two-year chance.
- However, these same business types at the worst locations in Greater Uptown can sometimes provide a projected Survivability Score considerably below the average. Thus, even the businesses that are most in need in Greater Uptown could have trouble succeeding if the best location is not selected.
- StreetSpring's model reads Greater Uptown's 13.0% housing vacancy rate, a Census measure of vacant homes and apartments, as one input among many.
Employment and housing vacancy figures sourced from the U.S. Census Bureau American Community Survey.
How can you find the best location to open a business in Greater Uptown?
StreetSpring narrows the decision down to the exact address, showing which blocks in Greater Uptown produce the highest survivability scores for your concept. Of all available storefronts analyzed in Greater Uptown, StreetSpring ranks this area highest for a Psychiatry or Psychology Practice in 2026:
The highlighted area represents the address in Greater Uptown that StreetSpring's 2026 analysis ranks highest for a Psychiatry or Psychology Practice survivability. These figures represent averages across a neighborhood; your specific address may score meaningfully higher or lower depending on block-level competitive conditions. StreetSpring's scoring incorporates hundreds of inputs, including competitive quality and density, projected consumer spending, Revenue Capture Score, and local demand patterns.
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What are the best businesses to open in Greater Uptown?
| # | Business type | Chance of lasting two or more years at a good address |
|---|---|---|
| 1 | Mental Health Clinic | 90.0% |
| 2 | Dentist Office | 90.0% |
| 3 | Physical Therapy Clinic | 90.0% |
| 6 | Eye Care Center | 90.0% |
| 8 | Veterinary Clinic | 88.3% |
| 9 | Day Care Center | 85.6% |
| 10 | Dance Club | 85.1% |
| 11 | Florist | 85.0% |
| 12 | Women's Clothing Store | 85.0% |
| 21 | Smoke Shop | 84.6% |
Ties at a good address: Mental Health Clinic, Dentist Office, Physical Therapy Clinic and Eye Care Center are tied; Florist and Women's Clothing Store are tied. A tie is a tie: the rank column is the published file's order, which looks at the average and the best address next.
The rank column is the published file's rank within this place; a skipped number is a business type the file ranks here that this list leaves out to keep any one business family from filling it.
Highest Survivability in Greater Uptown
- #1 Mental Health Clinic: 84.7% on average across Greater Uptown; best at 90.0%, challenging at 58.6%.
- #2 Opening a Dentist Office in Greater Uptown shows 83.8% average survivability. Top locations reach 90.0%; lower-end sites show 57.3%.
- #3 Physical Therapy Clinic (Ranked #3): 83.4% average in Greater Uptown. Best-case storefronts: 90.0%. Challenging locations: 56.8%.
- #6 Eye Care Center is ranked #6 for top businesses to open in Greater Uptown: 82.6% chance on average, best at 90.0%, challenging at 56.4%.
- #8 Veterinary Clinic: 76.8% on average across Greater Uptown; best at 89.2%, challenging at 56.0%.
Strong Performers in Greater Uptown
- #9 Opening a Day Care Center in Greater Uptown shows 74.8% average survivability. Top locations reach 86.0%; lower-end sites show 50.4%.
- #10 Dance Club (Ranked #10): 74.0% average in Greater Uptown. Best-case storefronts: 86.0%. Challenging locations: 50.0%.
- #11 Florist is ranked #11 for top businesses to open in Greater Uptown: 77.5% chance on average, best at 85.0%, challenging at 49.9%.
- #12 Women's Clothing Store: 77.5% on average across Greater Uptown; best at 85.0%, challenging at 49.9%.
- #21 Opening a Smoke Shop in Greater Uptown shows 73.1% average survivability. Top locations reach 85.0%; lower-end sites show 49.4%.
Top 3 Compared Nationally
- Mental Health Clinic: See how this compares to other cities →
- Dentist Office: See how this compares to other cities →
- Physical Therapy Clinic: See how this compares to other cities →
How much money could a business in Greater Uptown make?
Best location vs. average location
Based on StreetSpring's 2026 analysis, choosing an address that maximizes your Revenue Capture Score in Greater Uptown starts with the Revenue Capture Score, the most important factor in choosing a location: StreetSpring's estimate of the revenue a business can capture at that address.
How StreetSpring calculates location value
- Site selection requires evaluating the specific combination of your business type and the exact address: neighborhood-level data is only the starting point.
- The right location can make a business; the wrong one can break it.
- When the question is money, the Revenue Capture Score comes first: it is StreetSpring's estimate of the revenue a business can capture at a specific address.
- Our address-level scoring shows the exact survivability odds for 500+ business types at any given storefront.
What businesses should open next in Greater Uptown?
The top businesses to open next in Greater Uptown:
- Mental Health Clinics: 84.7% average survival rate, 90.0% at the best address
- Dentist Offices: 83.8% average survival rate
- Physical Therapy Clinics: 83.4% average survival rate
These figures represent averages across a neighborhood; your specific address may score meaningfully higher or lower depending on block-level competitive conditions. StreetSpring's training dataset includes millions of transactions and business lifecycle events. StreetSpring scores 500+ business types: 153 base business types, most of them at 5 price points, which is 569 type-and-price combinations you can choose in the tool. StreetSpring's model accounts for Greater Uptown's 93.6% employment rate when projecting survivability: businesses reliant on discretionary spend benefit disproportionately in well-employed neighborhoods. Survivability scores are live, not static: StreetSpring updates them regularly. Visit the tool to see what's currently available in Greater Uptown and how each address is scoring right now.
See the Survivability Score for your new business
Related Articles:
- See the Houston Business Survivability Rankings
- See the Houston Neighborhood Survivability Rankings
- Explore Mental Health Clinic survivability across Houston neighborhoods
Frequently Asked Questions
Here are the most common questions about opening a business in Greater Uptown.
What type of business should you rent your Greater Uptown storefront to?
For landlords in Greater Uptown, StreetSpring's 2026 analysis identifies Mental Health Clinics, Dentist Offices, and Physical Therapy Clinics as the business types most likely to produce stable, long-term tenancy.
- The right location can make a business; the wrong one can break it.
- Our address-level scoring shows the exact survivability odds for 500+ business types at any given storefront. StreetSpring can show you which specific address in your portfolio scores highest for each tenant type.
Related: See How Landlord Representatives in Houston Can Reduce Vacancy & Increase Tenant Longevity
Should you rent your Greater Uptown storefront to a Psychiatry or Psychology Practice?
Yes, our 2026 model places a Psychiatry or Psychology Practice at the top of the survivability rankings for Greater Uptown storefronts, with a best-case score of 90.0% and a floor of 58.6% at the most challenging addresses.
- Our address-level scoring shows the exact survivability odds for 500+ business types at any given storefront.
What should I consider when opening a business in Greater Uptown?
In Greater Uptown, the first step in your site-selection decision is checking the Survivability Score of the specific address you're evaluating.
- Revenue Capture is where competition meets spending, and it's the number that matters most when choosing a location.
- These forecasts are generated using StreetSpring's unique analytical framework.
- Start a free 10-minute trial on StreetSpring to see the current survivability score for any address in Greater Uptown.
See the best place for your business at StreetSpring.
StreetSpring's models are built from millions of real business outcomes, making predictions grounded in what actually happened. Aggregated survivability rankings for Houston are available in machine-readable format for research and integration purposes.
Full dataset for Houston: /resources/data/houston-survivability-scores-2026.csv: includes all business subtypes, all neighborhoods, survivability scores, and tier assignments. Licensed under CC BY 4.0.