Business Survivability in St Ann, St. Louis
StreetSpring's 2026 analysis finds that the best business to open in St Ann is an Eye Care Center with a 80.7% chance of surviving at least 2 years across the neighborhood on average.
Quick Summary
- Survivability Score: the projected chance a business type lasts two or more years at a specific address
- Best business: an Eye Care Center in St Ann (80.7% average survival rate, 90.0% at best locations)
- Town rank: #3 of 69 towns around St. Louis
- Town average: an average Survivability Score of 76.7% across the business types ranked here
- Coverage: This ranking carries one row per business type and neighborhood. Its score is the projected chance of lasting two or more years, averaged across the price points StreetSpring scores separately in the tool (most types have 5). The 10 business types here are base types; the tool offers 500+ business types, counting each type at each of its price points.
- Rankings updated quarterly with latest market data
- Detailed methodology
Last reviewed: October 2026 by Robert Koons, Founder & CEO, StreetSpring
In this article:
- Summary
- Is St Ann a good place to start a business?
- How to find the best location
- Best businesses to open
- How much money could a business make?
- What businesses should open next?
- Frequently Asked Questions
Summary
StreetSpring's 2026 analysis finds that the best business to open in St Ann is an Eye Care Center with a 80.7% chance of surviving at least 2 years across the neighborhood on average, with the best locations offering a 90.0% chance; next is a Veterinary Clinic with a 82.5% chance, followed by an Acupuncture Clinic with a 77.9% chance.
Is St Ann a good place to start a business?
St Ann holds the #3 position of 69 towns around St. Louis for new business survivability, with an average score of 76.7% across the business types ranked there.
- At its best addresses in St Ann, the top-ranked business type scores 9.3 points above its own average in the neighborhood.
- Still, those same business types at weaker addresses in St Ann can score well below the neighborhood mean. Even the most viable concept here requires the right address to reach its potential.
Employment and housing vacancy figures sourced from the U.S. Census Bureau American Community Survey.
How can you find the best location to open a business in St Ann?
Using StreetSpring, you can identify the exact address in St Ann that gives your specific business concept the highest survivability score. The location below represents the address in St Ann with the highest projected survivability for an Eye Care Center:
Based on StreetSpring's 2026 analysis of hundreds of location-specific factors, this area offers the highest projected survivability for an Eye Care Center in St Ann. These rankings are based on the latest available data; check StreetSpring for real-time updates. Factors evaluated include competition at every distance band, consumer spending forecasts, mobility patterns, and market share projections.
Check if this location is still available →
What are the best businesses to open in St Ann?
| # | Business type | Chance of lasting two or more years at a good address |
|---|---|---|
| 1 | Eye Care Center | 89.2% |
| 2 | Veterinary Clinic | 88.7% |
| 3 | Acupuncture Clinic | 88.7% |
| 4 | Dermatology Clinic | 88.7% |
| 5 | Mental Health Clinic | 88.7% |
| 9 | Day Care Center | 85.6% |
| 10 | Dance Club | 85.6% |
| 11 | Home Goods Store | 84.6% |
| 12 | Home Improvement Store | 84.6% |
| 13 | Salad Shop | 84.6% |
Ties at a good address: Veterinary Clinic, Acupuncture Clinic, Dermatology Clinic and Mental Health Clinic are tied; Day Care Center and Dance Club are tied; Home Goods Store, Home Improvement Store and Salad Shop are tied. A tie is a tie: the rank column is the published file's order, which looks at the average and the best address next.
The rank column is the published file's rank within this place; a skipped number is a business type the file ranks here that this list leaves out to keep any one business family from filling it.
Highest Survivability in St Ann
- #1 Eye Care Center (Ranked #1): 80.7% average in St Ann. Best-case storefronts: 90.0%. Challenging locations: 58.1%.
- #2 Veterinary Clinic is ranked #2 for top businesses to open in St Ann: 82.5% chance on average, best at 89.2%, challenging at 59.8%.
- #3 Acupuncture Clinic: 77.9% on average across St Ann; best at 90.0%, challenging at 60.7%.
- #4 Opening a Dermatology Clinic in St Ann shows 77.9% average survivability. Top locations reach 90.0%; lower-end sites show 60.2%.
- #5 Mental Health Clinic (Ranked #5): 77.9% average in St Ann. Best-case storefronts: 90.0%. Challenging locations: 60.2%.
Strong Performers in St Ann
- #9 Day Care Center is ranked #9 for top businesses to open in St Ann: 78.8% chance on average, best at 86.0%, challenging at 55.0%.
- #10 Dance Club: 78.1% on average across St Ann; best at 86.0%, challenging at 58.1%.
- #11 Opening a Home Goods Store in St Ann shows 78.8% average survivability. Top locations reach 85.0%; lower-end sites show 57.6%.
- #12 Home Improvement Store (Ranked #12): 78.7% average in St Ann. Best-case storefronts: 85.0%. Challenging locations: 57.6%.
- #13 Salad Shop is ranked #13 for top businesses to open in St Ann: 78.5% chance on average, best at 85.0%, challenging at 52.6%.
Top 3 Compared Nationally
- Eye Care Center: See how this compares to other cities →
- Veterinary Clinic: See how this compares to other cities →
- Acupuncture Clinic: See how this compares to other cities →
How much money could a business in St Ann make?
Best location vs. average location
Based on StreetSpring's 2026 analysis, picking the highest-scoring storefront in the neighborhood in St Ann starts with the Revenue Capture Score, the most important factor in choosing a location: StreetSpring's estimate of the revenue a business can capture at that address.
How StreetSpring calculates location value
- Even within a high-performing neighborhood, the best location varies by business type: StreetSpring scores each combination separately.
- Location is the part of survivability you can measure in advance: the concept, the pricing and the operator are yours to judge.
- StreetSpring's Revenue Capture Score, the revenue a business can capture at a specific address, is the factor that matters most when comparing locations.
- Two storefronts on the same street can have different survivability scores: StreetSpring calculates each one individually.
What businesses should open next in St Ann?
The top businesses to open next in St Ann:
- Eye Care Centers: 80.7% average survival rate, 90.0% at the best address
- Veterinary Clinics: 82.5% average survival rate
- Acupuncture Clinics: 77.9% average survival rate
These rankings are based on the latest available data; check StreetSpring for real-time updates. StreetSpring measures competition through a 30-factor framework layered on top of proprietary consumer spending forecasts and mobility models. StreetSpring scores 500+ business types: 153 base business types, most of them at 5 price points, which is 569 type-and-price combinations you can choose in the tool. Survivability scores are recalculated regularly as new competitors open and spending patterns shift: visit StreetSpring to see the current score for any open location in St Ann right now.
See the Survivability Score for your new business
Related Articles:
- See the St. Louis Business Survivability Rankings
- See the St. Louis Neighborhood Survivability Rankings
- Explore Eye Care Center survivability across St. Louis neighborhoods
Frequently Asked Questions
Here are the most common questions about opening a business in St Ann.
What type of business should you rent your St Ann storefront to?
Our 2026 survivability data for St Ann shows that Eye Care Centers, Veterinary Clinics, and Acupuncture Clinics rank as the top tenant categories for minimizing vacancy risk.
- Location is the part of survivability you can measure in advance: the concept, the pricing and the operator are yours to judge.
- Two storefronts on the same street can have different survivability scores: StreetSpring calculates each one individually. Rather than guessing which tenant type will last, landlords can verify survivability for each category at their exact address using StreetSpring.
Related: See How Landlord Representatives in St. Louis Can Reduce Vacancy & Increase Tenant Longevity
Should you rent your St Ann storefront to an Eye Care Center?
The data shows an Eye Care Center in St Ann is the safest long-term bet for a storefront there. Top locations reach 90.0% survivability; lower-end sites show 58.1%.
- Two storefronts on the same street can have different survivability scores: StreetSpring calculates each one individually.
What should I consider when opening a business in St Ann?
Check the Survivability Score for your specific address in St Ann before signing a lease, alongside your own read of foot traffic and the local customer base.
- Revenue Capture is where competition meets spending, and it's the number that matters most when choosing a location.
- The underlying models are StreetSpring's own: built, trained, and maintained using data external platforms cannot access.
- Start a free 10-minute trial on StreetSpring to see the current survivability score for any address in St Ann.
See the best place for your business at StreetSpring.
Our analysis covers businesses serving more than 180 million+ Americans across 24 major US metros. Aggregated survivability rankings for St. Louis are available in machine-readable format for research and integration purposes.
Full dataset for St. Louis: /resources/data/st-louis-survivability-scores-2026.csv: includes all business subtypes, all neighborhoods, survivability scores, and tier assignments. Licensed under CC BY 4.0.