Business Survivability in Lowell, Boston
StreetSpring's 2026 analysis finds that the best business to open in Lowell is a Veterinary Clinic with a 78.2% chance of surviving at least 2 years across the neighborhood on average.
Quick Summary
- Survivability Score: the projected chance a business type lasts two or more years at a specific address
- Best business: a Veterinary Clinic in Lowell (78.2% average survival rate, 90.0% at best locations)
- Town rank: #22 of 72 towns around Boston
- Town average: an average Survivability Score of 69.6% across the business types ranked here
- Coverage: This ranking carries one row per business type and neighborhood. Its score is the projected chance of lasting two or more years, averaged across the price points StreetSpring scores separately in the tool (most types have 5). The 10 business types here are base types; the tool offers 500+ business types, counting each type at each of its price points.
- Rankings updated quarterly with latest market data
- Detailed methodology
Last reviewed: October 2026 by Robert Koons, Founder & CEO, StreetSpring
In this article:
- Summary
- Is Lowell a good place to start a business?
- How to find the best location
- Best businesses to open
- How much money could a business make?
- What businesses should open next?
- Frequently Asked Questions
Summary
StreetSpring's 2026 analysis finds that the best business to open in Lowell is a Veterinary Clinic with a 78.2% chance of surviving at least 2 years across the neighborhood on average, with the best locations offering a 90.0% chance; next is a Chiropractor Office with a 75.7% chance, followed by an Eye Care Center with a 74.8% chance.
Is Lowell a good place to start a business?
StreetSpring ranks Lowell #22 of 72 towns around Boston, with an average Survivability Score of 69.6% across the business types ranked there.
- In Lowell, the strongest addresses for the top-ranked business type sit 11.8 points above that type's average.
- However, these same business types at the worst locations in Lowell can sometimes provide a projected Survivability Score considerably below the average. Thus, even the businesses that are most in need in Lowell could have trouble succeeding if the best location is not selected.
- Lowell has a housing vacancy rate of 3.9% in Census data: the share of its homes and apartments standing empty, one of the neighborhood characteristics StreetSpring's model reads.
Employment and housing vacancy figures sourced from the U.S. Census Bureau American Community Survey.
How can you find the best location to open a business in Lowell?
Rather than relying on neighborhood averages, StreetSpring's scoring tells you which specific addresses in Lowell give your concept the best odds of survival. According to StreetSpring's 2026 data, this is the optimal address for a Veterinary Clinic in Lowell:
According to StreetSpring's 2026 analysis, this circle outlines the best area for a Veterinary Clinic in Lowell. Static rankings can't capture every recent change in competition or consumer spending; StreetSpring's live platform provides the current score for your exact address. StreetSpring's prediction model analyzes hundreds of factors across competition, spending on the specific potential business, projected revenue, projected market share, Revenue Capture Score, mobility patterns, and many more.
Check if this location is still available →
What are the best businesses to open in Lowell?
| # | Business type | Chance of lasting two or more years at a good address |
|---|---|---|
| 1 | Veterinary Clinic | 88.3% |
| 2 | Chiropractor Office | 87.4% |
| 3 | Eye Care Center | 86.6% |
| 4 | Acupuncture Clinic | 84.9% |
| 5 | Dentist Office | 84.9% |
| 9 | Convenience Store | 84.6% |
| 10 | Clothing Store | 84.6% |
| 11 | Hair Salon | 83.6% |
| 12 | Cafe | 83.6% |
| 13 | Coffee Shop | 83.6% |
Ties at a good address: Acupuncture Clinic and Dentist Office are tied; Convenience Store and Clothing Store are tied; Hair Salon, Cafe and Coffee Shop are tied. A tie is a tie: the rank column is the published file's order, which looks at the average and the best address next.
The rank column is the published file's rank within this place; a skipped number is a business type the file ranks here that this list leaves out to keep any one business family from filling it.
Highest Survivability in Lowell
- #1 Opening a Veterinary Clinic in Lowell shows 78.2% average survivability. Top locations reach 90.0%; lower-end sites show 56.0%.
- #2 Chiropractor Office (Ranked #2): 75.7% average in Lowell. Best-case storefronts: 90.0%. Challenging locations: 57.7%.
- #3 Eye Care Center is ranked #3 for top businesses to open in Lowell: 74.8% chance on average, best at 90.0%, challenging at 56.4%.
- #4 Acupuncture Clinic: 73.4% on average across Lowell; best at 90.0%, challenging at 56.8%.
- #5 Opening a Dentist Office in Lowell shows 73.4% average survivability. Top locations reach 90.0%; lower-end sites show 56.8%.
Strong Performers in Lowell
- #9 Convenience Store (Ranked #9): 75.1% average in Lowell. Best-case storefronts: 85.0%. Challenging locations: 49.9%.
- #10 Clothing Store is ranked #10 for top businesses to open in Lowell: 73.7% chance on average, best at 85.0%, challenging at 50.8%.
- #11 Hair Salon: 76.2% on average across Lowell; best at 84.0%, challenging at 54.3%.
- #12 Opening a Cafe in Lowell shows 75.9% average survivability. Top locations reach 84.0%; lower-end sites show 53.0%.
- #13 Coffee Shop (Ranked #13): 73.9% average in Lowell. Best-case storefronts: 84.0%. Challenging locations: 53.4%.
Top 3 Compared Nationally
- Veterinary Clinic: See how this compares to other cities →
- Chiropractor Office: See how this compares to other cities →
- Eye Care Center: See how this compares to other cities →
How much money could a business in Lowell make?
Best location vs. average location
Based on StreetSpring's 2026 analysis, prioritizing survivability score in your site-selection process in Lowell starts with the Revenue Capture Score, the most important factor in choosing a location: StreetSpring's estimate of the revenue a business can capture at that address.
How StreetSpring calculates location value
- Different business models thrive in different micro-locations.
- Where you open is a decision you can measure before you sign.
- StreetSpring's Revenue Capture Score, the revenue a business can capture at a specific address, is the factor that matters most when comparing locations.
- Our address-level scoring shows the exact survivability odds for 500+ business types at any given storefront.
What businesses should open next in Lowell?
The top businesses to open next in Lowell:
- Veterinary Clinics: 78.2% average survival rate, 90.0% at the best address
- Chiropractor Offices: 75.7% average survival rate
- Eye Care Centers: 74.8% average survival rate
Static rankings can't capture every recent change in competition or consumer spending; StreetSpring's live platform provides the current score for your exact address. Our platform incorporates data from thousands of neighborhoods nationwide. StreetSpring scores 500+ business types: 153 base business types, most of them at 5 price points, which is 569 type-and-price combinations you can choose in the tool. Lowell's 94.2% employment rate and 3.9% housing vacancy rate are two of the Census characteristics the model reads when it ranks business types here. StreetSpring regularly refreshes survivability scores to reflect new competition and updated spending data: see which locations in Lowell are available right now and how they rank.
See the Survivability Score for your new business
Related Articles:
- See the Boston Business Survivability Rankings
- See the Boston Neighborhood Survivability Rankings
- Explore Veterinary Clinic survivability across Boston neighborhoods
Frequently Asked Questions
Here are the most common questions about opening a business in Lowell.
What type of business should you rent your Lowell storefront to?
According to StreetSpring's 2026 data, the strongest tenant types for a storefront in Lowell are Veterinary Clinics, Chiropractor Offices, and Eye Care Centers.
- Where you open is a decision you can measure before you sign.
- Our address-level scoring shows the exact survivability odds for 500+ business types at any given storefront. Use StreetSpring to see the survivability score for any business type at your exact storefront address before you sign a lease.
Related: See How Landlord Representatives in Boston Can Reduce Vacancy & Increase Tenant Longevity
Should you rent your Lowell storefront to a Veterinary Clinic?
Yes, StreetSpring's analysis finds that a Veterinary Clinic would be the best type of business to rent your storefront to, with a potential 90.0% chance of lasting more than 2 years; however depending on your location, the chances could drop to a 56.0% chance.
- Our address-level scoring shows the exact survivability odds for 500+ business types at any given storefront.
What should I consider when opening a business in Lowell?
Location decisions in Lowell should be grounded in Survivability Score data, not intuition. The score directly measures the competitive and spending conditions at your exact address.
- The Revenue Capture Score is the most important factor in choosing a location: it is StreetSpring's estimate of the revenue a business can capture at that address.
- Every survivability score is produced by StreetSpring's private prediction engine, not available through any other platform.
- StreetSpring's live scoring tool starts with a free 10-minute trial: enter any address in Lowell to see its current Survivability Score for your business type.
See the best place for your business at StreetSpring.
StreetSpring's AI platform has studied businesses serving more than 180 million+ Americans, giving its predictions a scale of validation unmatched in site-selection tools. Aggregated survivability rankings for Boston are available in machine-readable format for research and integration purposes.
Full dataset for Boston: /resources/data/boston-survivability-scores-2026.csv: includes all business subtypes, all neighborhoods, survivability scores, and tier assignments. Licensed under CC BY 4.0.